Discovery

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Explore groundbreaking findings and innovative genetic research through Discovery Lab’s extensive publications, where science meets discovery.

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

Samstein, R.M., Lee, CH., Shoushtari, A.N. et al. Tumor mutational load predicts survival after immunotherapy across multiple cancer types. Nat Genet 51, 202–206 (2019).

Epigenetic variation impacts individual differences in the transcriptional response to influenza infection

Aracena, K.A., Lin, YL., Luo, K. et al. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nat Genet 56, 408–419 (2024).

Genome assemblies of 11 bamboo species highlight diversification induced by dynamic subgenome dominance

Ma, PF., Liu, YL., Guo, C. et al. Genome assemblies of 11 bamboo species highlight diversification induced by dynamic subgenome dominance. Nat Genet (2024).

Subspecific origin and haplotype diversity in the laboratory mouse

Yang, H., Wang, J., Didion, J. et al. Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet 43, 648–655 (2011).

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Kunkle, B.W., Grenier-Boley, B., Sims, R. et al. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet 51, 414–430 (2019).